Search on: DNA POLYMERASE I 
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Descriptor English:   DNA Polymerase I 
Descriptor Spanish:   ADN polimerasa I 
Descriptor Portuguese:   DNA Polimerase I 
Synonyms English:   DNA Dependent DNA Polymerase I
DNA Pol I
DNA Polymerase alpha
DNA-Dependent DNA Polymerase I
Klenow Fragment
Polymerase I, DNA
Polymerase alpha, DNA  
Tree Number:   D08.811.913.696.445.308.300.225
Definition English:   A DNA-dependent DNA polymerase characterized in prokaryotes and may be present in higher organisms. It has both 3'-5' and 5'-3' exonuclease activity, but cannot use native double-stranded DNA as template-primer. It is not inhibited by sulfhydryl reagents and is active in both DNA synthesis and repair. EC 2.7.7.7. 
History Note English:   84(77); for DNA POLYMERASE ALPHA use DNA POLYMERASE II 1982-97 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   4323 
Unique Identifier:   D004256 

Occurrence in VHL:
 

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